MARC details
| 000 -LEADER |
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| fixed length control field |
03742nam a22005657a 4500 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
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| fixed length control field |
230316s20232023 xxu||||| |||| 00| 0 eng d |
| 022 ## - INTERNATIONAL STANDARD SERIAL NUMBER |
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| International Standard Serial Number |
0002-9149 |
| 024 ## - OTHER STANDARD IDENTIFIER |
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| Standard number or code |
10.1016/j.amjcard.2022.11.041 [doi] |
| 024 ## - OTHER STANDARD IDENTIFIER |
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| Standard number or code |
PMC9770958 [pmc] |
| 024 ## - OTHER STANDARD IDENTIFIER |
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| Standard number or code |
S0002-9149(22)01237-1 [pii] |
| 040 ## - CATALOGING SOURCE |
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| Original cataloging agency |
Ovid MEDLINE(R) |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) |
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| PMID |
36563459 |
| 245 ## - TITLE STATEMENT |
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| Title |
The Evolving Impact of Myocardial Injury in Patients With COVID-19 Amid the Omicron Wave of the Pandemic. |
| 251 ## - Source |
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| Source |
American Journal of Cardiology. 190:54-60, 2023 Mar 01. |
| 252 ## - Abbreviated Source |
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| Abbreviated source |
Am J Cardiol. 190:54-60, 2023 Mar 01. |
| 253 ## - Journal Name |
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| Journal name |
The American journal of cardiology |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. |
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| Year |
2023 |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. |
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| Manufacturer |
FY2023 |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. |
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| Publication date |
2023 Mar 01 |
| 265 ## - SOURCE FOR ACQUISITION/SUBSCRIPTION ADDRESS [OBSOLETE] |
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| Publication status |
ppublish |
| 265 ## - SOURCE FOR ACQUISITION/SUBSCRIPTION ADDRESS [OBSOLETE] |
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| Medline status |
MEDLINE |
| 520 ## - SUMMARY, ETC. |
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| Abstract |
COVID-19 with myocardial injury, defined as troponin elevation, is associated with worse outcomes. The temporal changes in outcomes during various phases of the pandemic remain unclear. We evaluated outcomes during the Omicron phase compared with previous phases of the pandemic. We analyzed patients who were COVID-19-positive with evidence of myocardial injury who presented to the MedStar Health system (11 hospitals in Washington, District of Columbia, and Maryland) during phase 1 of the pandemic (March to June 2020), phase 2 (October 2020 to January 2021), and phase 3 (Omicron; December 2021 to March 2022), comparing their characteristics and outcomes. The primary end point was in-hospital mortality. The cohort included 2,079 patients admitted who were COVID-19 positive and for whom troponin was elevated (phase 1: n = 150, phase 2: n = 854, phase 3: n = 1,075). Baseline characteristics were similar overall. Inflammatory markers were significantly elevated in phase 1 compared with phases 2 and 3. The use of remdesivir and dexamethasone was highest in phase 2. In phase 3, 52.6% of patients were fully vaccinated. In-hospital mortality, though high, was lower in phase 3 than in phases 1 and 2 (59.3% vs 28.1% vs 23.3%; p <0.001). Patients who were vaccinated showed more favorable in-hospital outcomes than did those who were unvaccinated (18.3% vs 24.2%, p = 0.042). In conclusion, patients with COVID-19 with elevated troponin during phase 3 tended to have improved outcomes when compared with patients in earlier waves of the pandemic. This improvement could be attributed to the implementation of the COVID-19 vaccines, advances in COVID-19 treatment options, provider experience, and less virulent variants. Copyright © 2022 Elsevier Inc. All rights reserved. |
| 546 ## - LANGUAGE NOTE |
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| Language note |
English |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
*COVID-19 |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
*Heart Injuries |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
COVID-19 Vaccines |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
COVID-19/ep [Epidemiology] |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
Humans |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
Pandemics |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
Troponin |
| 651 ## - SUBJECT ADDED ENTRY--GEOGRAPHIC NAME |
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| Institution |
MedStar Heart & Vascular Institute |
| 651 ## - SUBJECT ADDED ENTRY--GEOGRAPHIC NAME |
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| Institution |
MedStar Washington Hospital Center |
| 656 ## - INDEX TERM--OCCUPATION |
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| Department |
Interventional Cardiology Fellowship |
| 657 ## - INDEX TERM--FUNCTION |
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| Medline publication type |
Journal Article |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
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| Local Authors |
Ben-Dor, Itsik |
| Institution Code |
MHVI |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
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| Local Authors |
Case, Brian C |
| Institution Code |
MHVI |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
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| Local Authors |
Cellamare, Matteo |
| Institution Code |
MHVI |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
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| Local Authors |
Hashim, Hayder |
| Institution Code |
MHVI |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
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| Local Authors |
Medranda, Giorgio |
| Institution Code |
MWHC |
| Program |
Interventional Cardiology Fellowship |
| Degree |
MD |
| Resident year |
Alumni |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
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| Local Authors |
Rappaport, Hank |
| Institution Code |
MHVI |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
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| Local Authors |
Rogers, Toby |
| Institution Code |
MHVI |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
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| Local Authors |
Satler, Lowell |
| Institution Code |
MHVI |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
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| Local Authors |
Shea, Corey |
| Institution Code |
MHVI |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
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| Local Authors |
Waksman, Ron |
| Institution Code |
MHVI |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
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| Local Authors |
Zhang, Cheng |
| Institution Code |
MHVI |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
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| Local Authors |
Zhu, Mason |
| Institution Code |
MHVI |
| 790 ## - Authors |
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| All authors |
Case BC |
| -- |
Shea C |
| -- |
Rappaport H |
| -- |
Cellamare M |
| -- |
Zhang C |
| -- |
Zhu M |
| -- |
Medranda GA |
| -- |
Satler LF |
| -- |
Ben-Dor I |
| -- |
Hashim H |
| -- |
Rogers T |
| -- |
Waksman R |
| 856 ## - ELECTRONIC LOCATION AND ACCESS |
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| DOI |
<a href="https://dx.doi.org/10.1016/j.amjcard.2022.11.041">https://dx.doi.org/10.1016/j.amjcard.2022.11.041</a> |
| Public note |
https://dx.doi.org/10.1016/j.amjcard.2022.11.041 |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
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| Koha item type |
Journal Article |
| Item type description |
Journal Article |
