Comparative effectiveness of intravenous and inhaled magnesium in acute asthma. (Record no. 12256)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 02234nam a22003137a 4500 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 160113s20132013 xxu||||| |||| 00| 0 eng d |
| 022 ## - INTERNATIONAL STANDARD SERIAL NUMBER | |
| International Standard Serial Number | 2042-6305 |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | Ovid MEDLINE(R) |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) | |
| PMID | 24236741 |
| 245 ## - TITLE STATEMENT | |
| Title | Comparative effectiveness of intravenous and inhaled magnesium in acute asthma. |
| 251 ## - Source | |
| Source | Journal of Comparative Effectiveness Research. 2(5):437-41, 2013 Sep. |
| 252 ## - Abbreviated Source | |
| Abbreviated source | J. comp. eff. res.. 2(5):437-41, 2013 Sep. |
| 253 ## - Journal Name | |
| Journal name | Journal of comparative effectiveness research |
| 266 ## - Date added to catalog | |
| Date added to catalog | 2016-01-13 |
| 520 ## - SUMMARY, ETC. | |
| Abstract | Evaluation of: Goodacre S, Cohen J, Bradburn M et al. Intravenous or nebulised magnesium sulphate versus standard therapy for severe acute asthma (3Mg trial): a double-blind, randomized controlled trial. Lancet Respir. Med. 1, 293-300 (2013). Acute exacerbations of asthma are common. The current recommended treatment approach to managing an acute asthma exacerbation is to administer a short-acting inhaled beta2-agonist (SABA). SABAs are rapidly effective but may not provide the bronchodilation needed to restore adequate lung function. Consequently, in severe acute asthma exacerbations, despite a standard approach to treatment including SABAs, hospitalization is common. Magnesium is a bronchodilator that may provide additional benefit to SABAs in managing acute asthma exacerbations. In this article, the comparative effectiveness of inhaled and intravenous magnesium in addition to standard therapy is evaluated in the management of severe acute asthma exacerbations. Although neither inhaled nor intravenous magnesium achieved the protocol-specified benefits, intravenous magnesium was associated with fewer hospitalizations and a trend for greater improvement in the symptom of breathlessness than inhaled magnesium. |
| 546 ## - LANGUAGE NOTE | |
| Language note | English |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | *Asthma/th [Therapy] |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Female |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Humans |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Male |
| 651 ## - SUBJECT ADDED ENTRY--GEOGRAPHIC NAME | |
| Institution | MedStar Washington Hospital Center |
| 656 ## - INDEX TERM--OCCUPATION | |
| Department | Medicine/Pulmonary-Critical Care |
| 657 ## - INDEX TERM--FUNCTION | |
| Medline publication type | Comment |
| 657 ## - INDEX TERM--FUNCTION | |
| Medline publication type | Journal Article |
| 700 ## - ADDED ENTRY--PERSONAL NAME | |
| Local Authors | Colice, Gene L |
| 790 ## - Authors | |
| All authors | Colice GL |
| 856 ## - ELECTRONIC LOCATION AND ACCESS | |
| DOI | <a href="http://dx.doi.org/10.2217/cer.13.55">http://dx.doi.org/10.2217/cer.13.55</a> |
| Public note | http://dx.doi.org/10.2217/cer.13.55 |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Koha item type | Journal Article |
| Item type description | Journal article |
| Withdrawn status | Lost status | Damaged status | Not for loan | Collection | Home library | Current library | Date acquired | Total Checkouts | Barcode | Date last seen | Date last checked out | Price effective from | Koha item type |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MedStar Authors Catalog | MedStar Authors Catalog | 01/13/2016 | 1 | 24236741 | 09/26/2017 | 09/26/2017 | 01/13/2016 | Journal Article |