MARC details
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| fixed length control field |
04457nam a22003977a 4500 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
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231004s20232023 xxu||||| |||| 00| 0 eng d |
| 022 ## - INTERNATIONAL STANDARD SERIAL NUMBER |
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| International Standard Serial Number |
2561-326X |
| 024 ## - OTHER STANDARD IDENTIFIER |
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| Standard number or code |
10.2196/46034 [doi] |
| 024 ## - OTHER STANDARD IDENTIFIER |
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| Standard number or code |
v7i1e46034 [pii] |
| 040 ## - CATALOGING SOURCE |
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| Original cataloging agency |
Ovid MEDLINE(R) |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) |
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| PMID |
37566445 |
| 245 ## - TITLE STATEMENT |
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| Title |
Exploring the Impact of Dawn Phenomenon on Glucose-Guided Eating Thresholds in Individuals With Type 2 Diabetes Using Continuous Glucose Monitoring: Observational Study. |
| 251 ## - Source |
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| Source |
JMIR Formative Research. 7:e46034, 2023 Aug 11. |
| 252 ## - Abbreviated Source |
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| Abbreviated source |
JMIR Form Res. 7:e46034, 2023 Aug 11. |
| 253 ## - Journal Name |
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| Journal name |
JMIR formative research |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. |
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| Year |
2023 |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. |
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| Manufacturer |
FY2024 |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. |
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| Publication date |
2023 Aug 11 |
| 265 ## - SOURCE FOR ACQUISITION/SUBSCRIPTION ADDRESS [OBSOLETE] |
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| Publication status |
epublish |
| 265 ## - SOURCE FOR ACQUISITION/SUBSCRIPTION ADDRESS [OBSOLETE] |
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| Medline status |
Publisher |
| 266 ## - Date added to catalog |
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| Date added to catalog |
2023-10-04 |
| 520 ## - SUMMARY, ETC. |
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| Abstract |
BACKGROUND: Glucose-guided eating (GGE) improves metabolic markers of chronic disease risk, including insulin resistance, in adults without diabetes. GGE is a timed eating paradigm that relies on experiencing feelings of hunger and having a preprandial glucose level below a personalized threshold computed from 2 consecutive morning fasting glucose levels. The dawn phenomenon (DP), which results in elevated morning preprandial glucose levels, could cause typically derived GGE thresholds to be unacceptable or ineffective among people with type 2 diabetes (T2DM). |
| 520 ## - SUMMARY, ETC. |
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| Abstract |
CONCLUSIONS: DP was experienced by most study participants regardless of last eating times. The magnitude of the within-person effect of DP on morning preprandial glucose levels was meaningful in the context of GGE. Alternative approaches for determining acceptable and effective GGE thresholds for people with T2DM should be explored and evaluated. Copyright ©Michelle R Jospe, Kari M Marano, Arianna R Bedoya, Nick L Behrens, Lacey Cigan, Vanessa Villegas, Michelle F Magee, David G Marrero, Kelli M Richardson, Yue Liao, Susan M Schembre. Originally published in JMIR Formative Research (https://formative.jmir.org), 11.08.2023. |
| 520 ## - SUMMARY, ETC. |
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| Abstract |
METHODS: Study participants wore a single-blinded Dexcom G6 Pro continuous glucose monitoring (CGM) system for up to 10 days. First and last eating times and any overnight eating were reported using daily surveys over the study duration. DP was expressed as a dichotomous variable at the day level (DP day vs non-DP day) and as a continuous variable reflecting the percent of days DP was experienced on a valid day. A valid day was defined as having no reported overnight eating (between midnight and 6 AM). Glucose was computed as the difference in nocturnal glucose nadir (between midnight and 6 AM) to morning preprandial glucose levels. Glucose >=20 mg/dL constituted a DP day. Using multilevel modeling, we examined the between- and within-person effects of DP on morning preprandial glucose and the effect of evening eating times on DP. |
| 520 ## - SUMMARY, ETC. |
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| Abstract |
OBJECTIVE: The aim of this study is to quantify the incidence and day-to-day variability in the magnitude of DP and examine its effect on morning preprandial glucose levels as a preliminary test of the feasibility of GGE in adults with T2DM. |
| 520 ## - SUMMARY, ETC. |
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| Abstract |
RESULTS: In total, 21 adults (59% female; 13/21, 62%) with non-insulin-treated T2DM wore a CGM for an average of 10.5 (SD 1.1) days. Twenty out of 21 participants (95%) experienced DP for at least 1 day, with an average of 51% of days (SD 27.2; range 0%-100%). The mean glucose was 23.7 (SD 13.2) mg/dL. People who experience DP more frequently had a morning preprandial glucose level that was 54.1 (95% CI 17.0-83.9; P<.001) mg/dL higher than those who experienced DP less frequently. For within-person effect, morning preprandial glucose levels were 12.1 (95% CI 6.3-17.8; P=.008) mg/dL higher on a DP day than on a non-DP day. The association between glucose and preprandial glucose levels was 0.50 (95% CI 0.37-0.60; P<.001). There was no effect of the last eating time on DP. |
| 546 ## - LANGUAGE NOTE |
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| Language note |
English |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
IN PROCESS -- NOT YET INDEXED |
| 651 ## - SUBJECT ADDED ENTRY--GEOGRAPHIC NAME |
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| Institution |
MedStar Health Research Institute |
| 657 ## - INDEX TERM--FUNCTION |
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| Medline publication type |
Journal Article |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
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| Local Authors |
Magee, Michelle |
| Institution Code |
MHRI |
| 790 ## - Authors |
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| All authors |
Bedoya AR, Behrens NL, Cigan L, Jospe MR, Liao Y, Magee MF, Marano KM, Marrero DG, Richardson KM, Schembre SM, Villegas V |
| 856 ## - ELECTRONIC LOCATION AND ACCESS |
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| DOI |
<a href="https://dx.doi.org/10.2196/46034">https://dx.doi.org/10.2196/46034</a> |
| Public note |
https://dx.doi.org/10.2196/46034 |
| 858 ## - ORCID |
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| Name |
https://orcid.org/0000-0002-4692-3201 |
| ORCID text |
Magee, Michelle F |
| Orcid |
<a href="https://orcid.org/0000-0002-4692-3201">https://orcid.org/0000-0002-4692-3201</a> |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
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| Koha item type |
Journal Article |
| Item type description |
Article |
