MARC details
| 000 -LEADER |
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| fixed length control field |
03615nam a22005897a 4500 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
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| fixed length control field |
170428s20172017 xxu||||| |||| 00| 0 eng d |
| 022 ## - INTERNATIONAL STANDARD SERIAL NUMBER |
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| International Standard Serial Number |
0021-972X |
| 040 ## - CATALOGING SOURCE |
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| Original cataloging agency |
Ovid MEDLINE(R) |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) |
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| PMID |
28323961 |
| 245 ## - TITLE STATEMENT |
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| Title |
Normalized early post-operative cortisol and ACTH values predict nonremission after surgery for Cushing's disease. |
| 251 ## - Source |
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| Source |
Journal of Clinical Endocrinology & Metabolism. 102(7):2179-2187, 2017 Jul 01 |
| 252 ## - Abbreviated Source |
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| Abbreviated source |
J Clin Endocrinol Metab. 102(7):2179-2187, 2017 Jul 01 |
| 253 ## - Journal Name |
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| Journal name |
The Journal of clinical endocrinology and metabolism |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. |
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| Year |
2017 |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. |
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| Manufacturer |
FY2018 |
| 266 ## - Date added to catalog |
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| Date added to catalog |
2017-05-06 |
| 501 ## - WITH NOTE |
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| Local holdings |
Available online through MWHC library: 1999- June 2013, Available in print through MWHC library: 1999 - 2006 |
| 520 ## - SUMMARY, ETC. |
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| Abstract |
Conclusions: NEPV for cortisol and ACTH predict non-remission after TSS for CD. |
| 520 ## - SUMMARY, ETC. |
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| Abstract |
Context: Perioperative increases in adrenocorticotropic hormone (ACTH) and cortisol mimic corticotropin releasing hormone (CRH) stimulation testing. This phenomenon may help identify patients with residual adenoma after transsphenoidal surgery (TSS) for Cushing's disease (CD). |
| 520 ## - SUMMARY, ETC. |
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| Abstract |
Design: Retrospective case control study of patients treated at a single center from December 2003 till July 2016. Early and medium-term remission were assessed at 10 days and 11 months. |
| 520 ## - SUMMARY, ETC. |
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| Abstract |
Interventions: Normalized early post-operative values (NEPV) for cortisol and ACTH were calculated as immediate post-operative cortisol or ACTH minus preoperative post-CRH stimulation test levels. |
| 520 ## - SUMMARY, ETC. |
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| Abstract |
Main Outcome Measures: Prediction of early non-remission was evaluated using logistic regression. Prediction of medium-term remission was assessed using Cox regression. Predictive ability was quantified by areas under the receiver operating characteristic curve (AUROC). |
| 520 ## - SUMMARY, ETC. |
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| Abstract |
Objective: To predict non-remission after TSS for CD. |
| 520 ## - SUMMARY, ETC. |
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| Abstract |
Patients: 291 consecutive TSS cases from 257 patients with biochemical evidence of CD. |
| 520 ## - SUMMARY, ETC. |
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| Abstract |
Results: NEPV for cortisol and ACTH predicted early non-remission (adjusted OR 1.1, 95% CI 1.0 - 1.1, P = 0.016; and adjusted OR 1.0, 95% CI 1.0 - 1.0, P = 0.048 respectively). AUROC for NEPV cortisol was 0.78, 95% CI 0.61 - 0.95; and for NEPV ACTH was 0.80, 95% CI 0.61 - 0.98. NEPV for both cortisol and ACTH predicted medium-term non-remission (hazard ratios (HR) 1.1, 95% CI 1.0 - 1.1, P = 0.023; and HR 1.0, 95% CI 1.0 - 1.0, P = 0.025 respectively). |
| 520 ## - SUMMARY, ETC. |
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| Abstract |
Setting: Clinical Center. |
| 546 ## - LANGUAGE NOTE |
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| Language note |
English |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
*Adrenocorticotropic Hormone/bl [Blood] |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
*Hydrocortisone/bl [Blood] |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
*Pituitary ACTH Hypersecretion/su [Surgery] |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
Adult |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
Age Factors |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
Biomarkers/bl [Blood] |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
Female |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
Humans |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
Male |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
Pituitary ACTH Hypersecretion/bl [Blood] |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
Postoperative Period |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
Predictive Value of Tests |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
Prognosis |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
Reference Values |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
Remission Induction |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
Retrospective Studies |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
Sex Factors |
| 651 ## - SUBJECT ADDED ENTRY--GEOGRAPHIC NAME |
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| Institution |
MedStar Washington Hospital Center |
| 656 ## - INDEX TERM--OCCUPATION |
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| Department |
Medicine/Endocrinology |
| 657 ## - INDEX TERM--FUNCTION |
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| Medline publication type |
Journal Article |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
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| Local Authors |
Sharma, Susmeeta T |
| 790 ## - Authors |
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| All authors |
Asuzu D, Benzo S, Beri A, Chatain GP, Chittiboina P, Hayes C, Keil M, Lodish M, Lonser RR, McGlotten R, Nieman L, Oldfield EH, Sharma ST, Stratakis C |
| 856 ## - ELECTRONIC LOCATION AND ACCESS |
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| DOI |
<a href="https://dx.doi.org/10.1210/jc.2016-3908">https://dx.doi.org/10.1210/jc.2016-3908</a> |
| Public note |
https://dx.doi.org/10.1210/jc.2016-3908 |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
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| Koha item type |
Journal Article |
| Item type description |
Article |
