Effect of Function-Based Approach to Nontraumatic Major Lower Extremity Amputation on 5-Year Mortality. (Record no. 327)

MARC details
000 -LEADER
fixed length control field 04092nam a22005657a 4500
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 221018s20222022 xxu||||| |||| 00| 0 eng d
022 ## - INTERNATIONAL STANDARD SERIAL NUMBER
International Standard Serial Number 1072-7515
024 ## - OTHER STANDARD IDENTIFIER
Standard number or code 00019464-202209000-00010 [pii]
024 ## - OTHER STANDARD IDENTIFIER
Standard number or code 10.1097/XCS.0000000000000247 [doi]
040 ## - CATALOGING SOURCE
Original cataloging agency Ovid MEDLINE(R)
099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC)
PMID 35972163
245 ## - TITLE STATEMENT
Title Effect of Function-Based Approach to Nontraumatic Major Lower Extremity Amputation on 5-Year Mortality.
251 ## - Source
Source Journal of the American College of Surgeons. 235(3):438-446, 2022 Sep 01.
252 ## - Abbreviated Source
Abbreviated source J Am Coll Surg. 235(3):438-446, 2022 Sep 01.
253 ## - Journal Name
Journal name Journal of the American College of Surgeons
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Year 2022
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Manufacturer FY2023
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Publication date 2022 Sep 01
265 ## - SOURCE FOR ACQUISITION/SUBSCRIPTION ADDRESS [OBSOLETE]
Publication status ppublish
265 ## - SOURCE FOR ACQUISITION/SUBSCRIPTION ADDRESS [OBSOLETE]
Medline status MEDLINE
266 ## - Date added to catalog
Date added to catalog 2022-10-20
520 ## - SUMMARY, ETC.
Abstract BACKGROUND: Five-year mortality rates after lower extremity amputation in the chronic wound population have long been regarded as high and inevitable. We theorize that function-based surgical technique and multidisciplinary care improve mortality and assess our institution's mortality rates after major lower extremity amputation (MLEA).
520 ## - SUMMARY, ETC.
Abstract CONCLUSIONS: We demonstrate the lowest mortality rate reported for MLEA. Improved functional and mortality outcomes can be achieved with a function-based surgical approach to MLEA and close follow-up by a multidisciplinary team. Future studies, using standardized reporting of mortality data and incorporating patient-reported outcomes, are warranted to correlate return to function and mortality. Copyright © 2022 by the American College of Surgeons. Published by Wolters Kluwer Health, Inc. All rights reserved.
520 ## - SUMMARY, ETC.
Abstract RESULTS: A total of 188 patients underwent MLEA. Median Charlson Comorbidity Index was 4. Estimated 5-year mortality was 40% overall and 43% for diabetic patients. When stratified by amputation level, 5-year mortalities were 36.3% for below knee amputation, 60.9% for through knee amputation, and 44.0% for above knee amputation. Charlson Comorbidity Index (hazard ratio 1.24, p < 0.001) and end-stage renal disease (hazard ratio 3.38, p < 0.001) were the strongest predictors of 5-year mortality.
520 ## - SUMMARY, ETC.
Abstract STUDY DESIGN: We performed a retrospective review of patients who underwent primary nontraumatic MLEA at our institution from 2010 to 2013. Major amputations included below knee amputation, through knee amputation, and above knee amputation. Our function-based surgical approach to MLEA is guided by 4 tenets: (1) optimization of limb biomechanics, (2) maximal soft tissue preservation, (3) multidisciplinary team approach, and (4) addressing nerves during primary amputation to prevent postamputation pain. Kaplan-Meier analysis and Cox regression were performed to estimate cumulative 5-year mortality and to identify predictors of 5-year mortality, respectively.
546 ## - LANGUAGE NOTE
Language note English
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element *Amputation
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element *Lower Extremity
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Amputation/mt [Methods]
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Humans
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Lower Extremity/su [Surgery]
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Retrospective Studies
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Risk Factors
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Time Factors
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Treatment Outcome
651 ## - SUBJECT ADDED ENTRY--GEOGRAPHIC NAME
Institution MedStar Washington Hospital Center
656 ## - INDEX TERM--OCCUPATION
Department MedStar General Surgery Residency
656 ## - INDEX TERM--OCCUPATION
Department MedStar Georgetown University Hospital/MedStar Washington Hospital Center
656 ## - INDEX TERM--OCCUPATION
Department Plastic Surgery Residency
656 ## - INDEX TERM--OCCUPATION
Department Plastic Surgery Residency
656 ## - INDEX TERM--OCCUPATION
Department Surgery/Plastic Surgery
657 ## - INDEX TERM--FUNCTION
Medline publication type Journal Article
700 ## - ADDED ENTRY--PERSONAL NAME
Local Authors Bekeny, Jenna
Institution Code MGUH
Program Plastic Surgery Residency
Degree MD
Resident year Resident PGY 2
700 ## - ADDED ENTRY--PERSONAL NAME
Local Authors Deldar, Romina
Institution Code MGUH
Program MedStar General Surgery Residency
Degree MD
Resident year Resident PGY 4
700 ## - ADDED ENTRY--PERSONAL NAME
Local Authors Fan, Kenneth L
Institution Code MWHC
700 ## - ADDED ENTRY--PERSONAL NAME
Local Authors Zolper, Elizabeth
Institution Code MGUH
Program Plastic Surgery Residency
Degree MD
Resident year Resident PGY 2
790 ## - Authors
All authors Attinger CE, Bekeny JC, Deldar R, Evans KK, Fan KL, Haffner ZK, Hill CB, Meshkin DH, Sayyed AA, Zolper EG
856 ## - ELECTRONIC LOCATION AND ACCESS
DOI <a href="https://dx.doi.org/10.1097/XCS.0000000000000247">https://dx.doi.org/10.1097/XCS.0000000000000247</a>
Public note https://dx.doi.org/10.1097/XCS.0000000000000247
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Koha item type Journal Article
Item type description Article
Holdings
Withdrawn status Lost status Damaged status Not for loan Collection Home library Current library Date acquired Total Checkouts Full call number Barcode Date last seen Price effective from Koha item type
          MedStar Authors Catalog MedStar Authors Catalog 10/20/2022   35972163 35972163 10/20/2022 10/20/2022 Journal Article

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