Multiple sclerosis relapse: Qualitative findings from clinician and patient interviews. (Record no. 3863)

MARC details
000 -LEADER
fixed length control field 03371nam a22004937a 4500
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 181108s20192019 xxu||||| |||| 00| 0 eng d
022 ## - INTERNATIONAL STANDARD SERIAL NUMBER
International Standard Serial Number 2211-0348
024 ## - OTHER STANDARD IDENTIFIER
Standard number or code 10.1016/j.msard.2018.09.029 [doi]
024 ## - OTHER STANDARD IDENTIFIER
Standard number or code S2211-0348(18)30350-X [pii]
040 ## - CATALOGING SOURCE
Original cataloging agency Ovid MEDLINE(R)
099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC)
PMID 30384199
245 ## - TITLE STATEMENT
Title Multiple sclerosis relapse: Qualitative findings from clinician and patient interviews.
245 ## - TITLE STATEMENT
Title Multiple sclerosis relapse: Qualitative findings from clinician and patient interviews.
251 ## - Source
Source Multiple Sclerosis and Related Disorders. 27:139-146, 2019 Jan.
252 ## - Abbreviated Source
Abbreviated source Mult Scler Relat Disord. 27:139-146, 2019 Jan.
253 ## - Journal Name
Journal name Multiple sclerosis and related disorders
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Year 2019
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Manufacturer FY2019
265 ## - SOURCE FOR ACQUISITION/SUBSCRIPTION ADDRESS [OBSOLETE]
Publication status aheadofprint
266 ## - Date added to catalog
Date added to catalog 2018-11-09
520 ## - SUMMARY, ETC.
Abstract BACKGROUND: In patients with relapsing forms of multiple sclerosis (MS), relapses are often unrecognized. These missed relapses have broad implications for the conduct of clinical trials as well as for the care and prognosis of people with multiple sclerosis (MS). With the ultimate goal of developing new methods to identify relapse, the purpose of this qualitative research with patients and clinicians was to examine the definition, symptoms, and impact of relapse.
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Abstract CONCLUSION: MS relapses, which have substantial impact on patient functioning, appear to include symptoms beyond those in typical definitions of relapse. Incorporating such constructs into new measures of relapse could lead to improved recognition of relapse episodes.
520 ## - SUMMARY, ETC.
Abstract Copyright (c) 2018 Elsevier B.V. All rights reserved.
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Abstract METHODS: This qualitative study involved semi-structured interviews with clinicians specializing in MS and people with relapsing-remitting (RR) MS. A brief literature review was conducted to inform the development of interview guides. Qualitative data were gathered from 10 clinicians in a series of individual interviews and one focus group, followed by a series of interviews with 20 patients. Thematic analysis was conducted using ATLAS.ti to identify concepts emerging from the interviews.
520 ## - SUMMARY, ETC.
Abstract RESULTS: Both clinicians and people with MS tend to describe classic neurologic symptoms that are confirmable on exam as indicative of relapses (e.g., sensory changes, vision issues, and walking difficulties), while also acknowledging that several less quantifiable symptoms are common (e.g., fatigue, pain, and cognitive issues). Patients described far-reaching impacts of relapse beyond just the quantifiable manifestations of the disease evaluated by commonly-used measures of MS severity and disability.
546 ## - LANGUAGE NOTE
Language note English
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element *Disease Progression
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Topical term or geographic name entry element *Multiple Sclerosis, Relapsing-Remitting/pp [Physiopathology]
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Topical term or geographic name entry element Adult
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Topical term or geographic name entry element Female
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Topical term or geographic name entry element Humans
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Male
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Topical term or geographic name entry element Middle Aged
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Neurologists
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Patients
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Qualitative Research
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Recurrence
651 ## - SUBJECT ADDED ENTRY--GEOGRAPHIC NAME
Institution MedStar Health Research Institute
657 ## - INDEX TERM--FUNCTION
Medline publication type Journal Article
700 ## - ADDED ENTRY--PERSONAL NAME
Local Authors Chan, Kitty
790 ## - Authors
All authors Chan KS, Kim K, Matza LS, Mowry EM, Phillips G, Smith KC, Zorn K
856 ## - ELECTRONIC LOCATION AND ACCESS
DOI <a href="https://dx.doi.org/10.1016/j.msard.2018.09.029">https://dx.doi.org/10.1016/j.msard.2018.09.029</a>
Public note https://dx.doi.org/10.1016/j.msard.2018.09.029
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Koha item type Journal Article
Item type description Article
Holdings
Withdrawn status Lost status Damaged status Not for loan Collection Home library Current library Date acquired Total Checkouts Full call number Barcode Date last seen Price effective from Koha item type
          MedStar Authors Catalog MedStar Authors Catalog 11/09/2018   30384199 30384199 11/09/2018 11/09/2018 Journal Article

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