MARC details
| 000 -LEADER |
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| fixed length control field |
04437nam a22006137a 4500 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
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| fixed length control field |
220124s20212021 xxu||||| |||| 00| 0 eng d |
| 022 ## - INTERNATIONAL STANDARD SERIAL NUMBER |
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| International Standard Serial Number |
2405-500X |
| 024 ## - OTHER STANDARD IDENTIFIER |
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| Standard number or code |
10.1016/j.jacep.2021.04.004 [doi] |
| 024 ## - OTHER STANDARD IDENTIFIER |
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| Standard number or code |
NIHMS1697386 [mid] |
| 024 ## - OTHER STANDARD IDENTIFIER |
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| Standard number or code |
PMC8605982 [pmc] |
| 024 ## - OTHER STANDARD IDENTIFIER |
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| Standard number or code |
S2405-500X(21)00329-7 [pii] |
| 040 ## - CATALOGING SOURCE |
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| Original cataloging agency |
Ovid MEDLINE(R) |
| 099 ## - LOCAL FREE-TEXT CALL NUMBER (OCLC) |
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| PMID |
34217663 |
| 245 ## - TITLE STATEMENT |
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| Title |
Predictors of Major Atrial Fibrillation Endpoints in the National Heart, Lung, and Blood Institute HCMR. |
| 251 ## - Source |
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| Source |
JACC. Clinical Electrophysiology. 7(11):1376-1386, 2021 11. |
| 252 ## - Abbreviated Source |
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| Abbreviated source |
JACC Clin Electrophysiol. 7(11):1376-1386, 2021 11. |
| 252 ## - Abbreviated Source |
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| Former abbreviated source |
JACC Clin Electrophysiol. 7(11):1376-1386, 2021 11. |
| 252 ## - Abbreviated Source |
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| Former abbreviated source |
JACC Clin Electrophysiol. 7(11):1376-1386, 2021 Nov. |
| 253 ## - Journal Name |
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| Journal name |
JACC. Clinical electrophysiology |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. |
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| Year |
2021 |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. |
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| Manufacturer |
FY2022 |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. |
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| Publication date |
2021 Nov |
| 265 ## - SOURCE FOR ACQUISITION/SUBSCRIPTION ADDRESS [OBSOLETE] |
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| Publication status |
ppublish |
| 266 ## - Date added to catalog |
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| Date added to catalog |
2021-07-26 |
| 268 ## - Previous citation |
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| -- |
JACC. Clinical Electrophysiology. 7(11):1376-1386, 2021 11. |
| 268 ## - Previous citation |
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| -- |
JACC. Clinical Electrophysiology. 7(11):1376-1386, 2021 Nov. |
| 269 ## - Original dates |
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| Original fiscal year |
FY2022 |
| 520 ## - SUMMARY, ETC. |
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| Abstract |
BACKGROUND: Atrial fibrillation (AF) is a common morbidity associated with hypertrophic cardiomyopathy (HCM). The HCMR (Hypertrophic Cardiomyopathy Registry) trial is a prospective natural history study of 2,755 patients with HCM with comprehensive phenotyping. |
| 520 ## - SUMMARY, ETC. |
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| Abstract |
CONCLUSIONS: The major predictors of major AF endpoints in HCM include older age, high BMI, moderate or severe MR, history of arrhythmia, increased LA volume, and reduced LA contractile percent. Prospective testing of a risk score based on these parameters may be warranted. Copyright (c) 2021 American College of Cardiology Foundation. Published by Elsevier Inc. All rights reserved. |
| 520 ## - SUMMARY, ETC. |
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| Abstract |
METHODS: All patients received yearly telephone follow-up. Major AF endpoints were defined as requiring electrical cardioversion, catheter ablation, hospitalization for >24 h, or clinical decisions to accept permanent AF. Penalized regression via elastic-net methodology identified the most important predictors of major AF endpoints from 46 variables. This was applied to 10 datasets, and the variables were ranked. Predictors that appeared in all 10 sets were then used in a Cox model for competing risks and analyzed as time to first event. |
| 520 ## - SUMMARY, ETC. |
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| Abstract |
OBJECTIVES: This study sought to identify predictors of major clinically important atrial fibrillation endpoints in hypertrophic cardiomyopathy. |
| 520 ## - SUMMARY, ETC. |
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| Abstract |
RESULTS: Data from 2,631 (95.5%) patients were available for analysis after exclusions. A total of 127 major AF endpoints events occurred in 96 patients over 33.3 +/- 12.4 months. In the final model, age, body mass index (BMI), left atrial (LA) volume index, LA contractile percent (active contraction), moderate or severe mitral regurgitation (MR), and history of arrhythmia the most important. BMI, LA volume index, and LA contractile percent were age-dependent. Obesity was a stronger risk factor in younger patients. Increased LA volume, reduced LA contractile percent, and moderate or severe MR put middle-aged and older adult patients at increased risk. |
| 546 ## - LANGUAGE NOTE |
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| Language note |
English |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
*Atrial Fibrillation |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
*Catheter Ablation |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
Aged |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
Atrial Fibrillation/su [Surgery] |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
Atrial Fibrillation/th [Therapy] |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
Heart Atria |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
Humans |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
Middle Aged |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
National Heart, Lung, and Blood Institute (U.S.) |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
Prospective Studies |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name entry element |
United States/ep [Epidemiology] |
| 651 ## - SUBJECT ADDED ENTRY--GEOGRAPHIC NAME |
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| Institution |
MedStar Health Research Institute |
| 651 ## - SUBJECT ADDED ENTRY--GEOGRAPHIC NAME |
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| Institution |
MedStar Heart & Vascular Institute |
| 657 ## - INDEX TERM--FUNCTION |
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| Medline publication type |
Journal Article |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
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| Local Authors |
Dolman, Sarahfaye F |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
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| Local Authors |
Kolm, Paul |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
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| Local Authors |
Weintraub, William S |
| 790 ## - Authors |
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| All authors |
Appelbaum E, Berry C, Bradlow W, Buccarelli-Ducci C, Casadei B, Chiribiri A, Choudhury L, Dawson DK, Desai MY, Desvigne-Nickens P, DiMarco JP, Dolman SF, Friedrich MG, Geller N, HCMR Investigators, Helms A, Ho CY, Jacoby D, Jerosch-Herold M, Kim DY, Kolm P, Kramer CM, Kwong RY, Mahmod M, Maron MS, Michels M, Nagueh SF, Neubauer S, Owens A, Piechnik SK, Salerno M, Schulz-Menger J, Watkins H, Weinsaft JW, Weintraub WS, White J |
| 856 ## - ELECTRONIC LOCATION AND ACCESS |
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| DOI |
<a href="https://dx.doi.org/10.1016/j.jacep.2021.04.004">https://dx.doi.org/10.1016/j.jacep.2021.04.004</a> |
| Public note |
https://dx.doi.org/10.1016/j.jacep.2021.04.004 |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
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| Koha item type |
Journal Article |
| Item type description |
Article |
