TY - BOOK AU - Allen, Elizabeth A AU - Haas, Christopher AU - Quarrie, Ricardo AU - Zuwasti, Ufara TI - Severe functional mitral stenosis due to a left atrial myxoma masquerading as asthma SN - 1757-790X PY - 2020/// KW - *Dyspnea/et [Etiology] KW - *Heart Neoplasms/di [Diagnosis] KW - *Mitral Valve Stenosis/di [Diagnosis] KW - *Myxoma/di [Diagnosis] KW - Asthma/di [Diagnosis] KW - Cardiopulmonary Bypass KW - Computed Tomography Angiography KW - Diagnosis, Differential KW - Dyspnea/su [Surgery] KW - Echocardiography KW - Electrocardiography KW - Female KW - Heart Atria/dg [Diagnostic Imaging] KW - Heart Atria/pa [Pathology] KW - Heart Neoplasms/co [Complications] KW - Heart Neoplasms/pa [Pathology] KW - Heart Neoplasms/su [Surgery] KW - Humans KW - Middle Aged KW - Mitral Valve Stenosis/et [Etiology] KW - Mitral Valve Stenosis/su [Surgery] KW - Myxoma/co [Complications] KW - Myxoma/pa [Pathology] KW - Myxoma/su [Surgery] KW - Sternotomy KW - Treatment Outcome KW - MedStar Franklin Square Medical Center KW - MedStar Heart & Vascular Institute KW - MedStar Union Memorial Hospital KW - Pathology KW - Journal Article N2 - While cardiac myxomas are the most common primary cardiac tumours, their overall incidence remains rare. Most cases (90%) are sporadic and occur in the third-sixth decades of life with a female predominance and have a specific predilection for the left atrium (75%). While often asymptomatic, clinical presentations depend on the tumour size, architecture and location. Echocardiography remains the mainstay for diagnostic evaluation. Tumour resection is the only definitive treatment. Histopathology using H&E and immunohistochemical stains, such as calretinin and CD34, confirms the diagnosis. We present a case of a patient with reported history of asthma who presented with recurrent acute on chronic shortness of breath refractory to inhaler therapy, multiple outpatient visits and hospitalisations for 'asthma exacerbations'. After further evaluation, she was diagnosed with a left atrial myxoma attached to the inferior aspect of the intra-atrial septum complicated by severe functional mitral stenosis. Copyright (c) BMJ Publishing Group Limited 2020. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ UR - https://dx.doi.org/10.1136/bcr-2020-236876 ER -