TY  - BOOK
AU  - Alnababteh, Muhtadi
AU  - Chopra, Rajus
AU  - Hashmi, Muhammad D
AU  - Hayat, Fatima
AU  - Kohli, Akshay
AU  - Kriner, Eric
AU  - Molina, Ezequiel
AU  - Oweis, Emil
AU  - Pratt, Alexandra
AU  - Vedantam, Karthik
AU  - Zaaqoq, Akram M
TI  - Extracorporeal membrane oxygenation for COVID-19 induced hypoxia: Single-center study
SN  - 0267-6591
PY  - 2021///
KW  - *COVID-19
KW  - *Extracorporeal Membrane Oxygenation
KW  - *Respiratory Distress Syndrome
KW  - Extracorporeal Membrane Oxygenation/ae [Adverse Effects]
KW  - Humans
KW  - Hypoxia
KW  - SARS-CoV-2
KW  - MedStar Heart & Vascular Institute
KW  - MedStar Washington Hospital Center
KW  - Medicine/Internal Medicine
KW  - Medicine/Pulmonary-Critical Care
KW  - Surgery/Surgical Critical Care
KW  - Journal Article
N2  - CONCLUSION: ECMO is a supportive intervention for COVID-19 associated pneumonia that could be considered if the optimum mechanical ventilation is deemed ineffective. Biomarkers such as D-dimer, LDH, and troponin could help with discerning the clinical prognosis in patients with COVID-19 pneumonia; INTRODUCTION: The pandemic of the coronavirus disease 2019 (COVID-19) and associated pneumonia represent a clinical and scientific challenge. The role of Extracorporeal Membrane Oxygenation (ECMO) in such a crisis remains unclear; METHODS: We examined COVID-19 patients who were supported for acute respiratory failure by both conventional mechanical ventilation (MV) and ECMO at a tertiary care institution in Washington DC. The study period extended from March 23 to April 29. We identified 59 patients who required invasive mechanical ventilation. Of those, 13 patients required ECMO; RESULTS: Nine out of 13 ECMO (69.2%) patients were decannulated from ECMO. All-cause ICU mortality was comparable between both ECMO and MV groups (6 patients [46.15%] vs. 22 patients [47.82 %], p = 0.92). ECMO non-survivors vs survivors had elevated D-dimer (9.740 mcg/ml [4.84-20.00] vs. 3.800 mcg/ml [2.19-9.11], p = 0.05), LDH (1158 +/- 344.5 units/L vs. 575.9 +/- 124.0 units/L, p = 0.001), and troponin (0.4315 +/- 0.465 ng/ml vs. 0.034 +/- 0.043 ng/ml, p = 0.04). Time on MV as expected was significantly longer in ECMO groups (563.3 hours [422.1-613.9] vs. 247.9 hours [101.8-479] in MV group, p = 0.0009) as well as ICU length of stay 576.2 hours [457.5-652.8] in ECMO group vs. 322.2 hours [120.6-569.3] in MV group, p = 0.012)
UR  - https://dx.doi.org/10.1177/0267659120963885
ER  -