TY  - BOOK
AU  - Driggers, Rita W
AU  - Feghali, Maisa N
AU  - Miodovnik, Menachem
AU  - Timofeev, Julia
TI  - Asymmetric large for gestational age newborns in pregnancies complicated by diabetes mellitus: is maternal obesity a culprit?
SN  - 1476-4954
KW  - *Diabetes Mellitus, Type 1/co [Complications]
KW  - *Diabetes Mellitus, Type 2/co [Complications]
KW  - *Fetal Macrosomia/ep [Epidemiology]
KW  - *Obesity/co [Complications]
KW  - *Pregnancy Complications
KW  - *Pregnancy in Diabetics
KW  - Adult
KW  - Birth Weight
KW  - Body Mass Index
KW  - Female
KW  - Fetal Macrosomia/et [Etiology]
KW  - Humans
KW  - Infant, Newborn
KW  - Insulin/ad [Administration & Dosage]
KW  - Pregnancy
KW  - Weight Gain
KW  - MedStar Health Research Institute
KW  - MedStar Washington Hospital Center
KW  - Obstetrics and Gynecology/Maternal-Fetal Medicine
KW  - Journal Article
KW  - Research Support, N.I.H., Extramural
KW  - Research Support, Non-U.S. Gov't
KW  - Research Support, U.S. Gov't, P.H.S
N1  - Available online through MWHC library: 2013 to the present
N2  - CONCLUSION: Although there is a known association between obesity and LGA in women with diabetes, we found that overweight and obese women with Type 1 or Type 2 diabetes do not have increased odds of delivering an A-LGA newborn. However, insulin dose in Type 2 diabetes and maternal weight gain in Type 1 diabetes were significantly associated with the odds of delivering an A-LGA neonate; METHODS: Retrospective analysis of 306 pregnancies complicated by Type 1 and 55 by Type 2 diabetes; OBJECTIVE: Evaluate the association between body mass index (BMI) and the delivery of an asymmetrically large for gestational age (A-LGA) newborn in women with diabetes; RESULTS: The prevalence of Type 1 and Type 2 diabetics delivering large for gestational age (LGA) infants was 42% and 49%, respectively. Of these 49% and 55% were A-LGA, respectively. Pre-pregnancy BMI was not associated with increased odds of delivering an A-LGA newborn in women with Type 1 or 2 diabetes. However, in Type 1 diabetics, each one-pound increase in maternal weight during pregnancy resulted in 4% increased odds of delivering an A-LGA newborn. For Type 2 diabetics, the odds of delivering an A-LGA infant was decreased by 10% for each 0.1 unit/kg increase in insulin dose
UR  - http://dx.doi.org/10.3109/14767058.2012.626925
ER  -