TY  - BOOK
AU  - Amini, Dennis
AU  - Driggers, Rita W
AU  - Huang, Chun Chih
AU  - Landy, Helain J
AU  - Miodovnik, Menachem
AU  - Singh, Jasbir
AU  - Timofeev, Julia
AU  - Umans, Jason G
TI  - The impact of pre-pregnancy body mass index on the risk of gestational diabetes
SN  - 1476-4954
PY  - 2012///
KW  - *Body Mass Index
KW  - *Diabetes, Gestational/ep [Epidemiology]
KW  - *Preconception Care
KW  - Case-Control Studies
KW  - Diabetes, Gestational/eh [Ethnology]
KW  - Ethnic Groups
KW  - Female
KW  - Humans
KW  - Hypertension
KW  - Logistic Models
KW  - National Institutes of Health (U.S.)
KW  - Obesity/co [Complications]
KW  - Obesity/di [Diagnosis]
KW  - Odds Ratio
KW  - Parity
KW  - Pregnancy
KW  - Pregnancy Complications
KW  - Risk Factors
KW  - United States
KW  - MedStar Health Research Institute
KW  - MedStar Washington Hospital Center
KW  - Obstetrics and Gynecology/Maternal-Fetal Medicine
KW  - Journal Article
KW  - Research Support, N.I.H., Extramural
KW  - Research Support, Non-U.S. Gov't
N1  - Available online through MWHC library: 2013 to the present
N2  - CONCLUSIONS: GDM is a multifactorial disorder and pre-pregnancy BMI plays an important role in that risk. Modest 130912s in pre-pregnancy BMI may decrease the risk of GDM substantially; METHODS: We performed a case control study using data collected in The Consortium on Safe Labor database. The association between BMI and GDM was evaluated both using BMI weight categories adopted by the National Institute of Health, and separately using BMI as a continuous variable. Multiple logistic regression analyses were used to evaluate the effects of BMI, age, ethnicity, parity, chronic hypertension and antenatal steroid use on the risk of GDM. Odds ratios (ORs) and 95% confidence intervals (CIs) were calculated to approximate relative risks of GDM. A p value of <0.05 was considered significant; OBJECTIVE: To evaluate the effect of pre-pregnancy body mass index (BMI) on the risk of developing gestational diabetes mellitus (GDM) in a large unselected population; RESULTS: After controlling for other factors, the risk of GDM increased with an increasing BMI across all weight categories. For each 1 kg/m(2) increase of BMI the OR of developing GDM was 1.08 (95% CI 1.08-1.09) and for each 5 kg/m(2) increase, the OR was 1.48 (95% CI 1.45-1.51)
UR  - http://dx.doi.org/10.3109/14767058.2012.626920
ER  -