TY - BOOK AU - Chisolm, Paul AU - Crossley, Jason AU - Pierce, Matthew TI - Perioperative complications among head and neck surgery patients with COVID-19 SN - 1043-3074 PY - 2023/// KW - *COVID-19 KW - *Head and Neck Neoplasms KW - *Myocardial Infarction KW - Head and Neck Neoplasms/co [Complications] KW - Head and Neck Neoplasms/su [Surgery] KW - Humans KW - Multicenter Studies as Topic KW - Myocardial Infarction/et [Etiology] KW - Postoperative Complications/ep [Epidemiology] KW - Postoperative Complications/et [Etiology] KW - Retrospective Studies KW - MedStar Washington Hospital Center KW - MedStar Georgetown University Hospital/MedStar Washington Hospital Center KW - Otolaryngology KW - Otolaryngology Residency KW - Journal Article N2 - BACKGROUND: Patients undergoing surgery for head and neck cancer (HNC) have potentially high perioperative complication rates. Recent studies indicate that preoperative COVID-19 infection poses increased risk for postoperative complications in other fields. However, to date, there has not been data showing the effect of COVID-19 on complication rates for HNC. Here, a large database was employed to assess if perioperative COVID-19 increased the risk of perioperative complications among those undergoing HNC surgery; CONCLUSION: This large, retrospective populational study suggests HNC patients are at increased risk for death and several perioperative complications. This investigation is the first to address this clinical question. Copyright © 2023 The Authors. Head & Neck published by Wiley Periodicals LLC; METHODS: A retrospective investigation was conducted using a multi-institutional research database. Subjects who underwent HNC surgery from January 2020 to September 2022 were identified using the International Classification of Diseases and Current Procedure Terminology codes. Thirty-day surgical and medical complications were assessed for those diagnosed with COVID-19 infection from 7 days before or after surgery compared to those who were COVID-19 negative. Cohorts were propensity scores matched by age, sex, and race; RESULTS: Perioperative COVID-19 was present in n = 208 and absent in n = 15 158 subjects that underwent HNC surgery. For unmatched analyses, there was a statistically significant increased risk in the 30-day postoperative period in COVID-19-positive patients for the following surgical complications: surgical site fistula, free tissue transfer (FTT) complication, FTT failure, and death. Additionally, there was a statistically significant increased risk in the 30-day postoperative period in COVID-19-positive patients for the following medical complications: ventilator support, pneumonia, vasopressor, acute renal failure, and myocardial infarction UR - https://dx.doi.org/10.1002/hed.27531 ER -