TY - BOOK AU - Taylor, Allen J AU - Utsunomiya, Daisuke AU - Weigold, William Guy AU - Weissman, Gaby TI - Effect of hybrid iterative reconstruction technique on quantitative and qualitative image analysis at 256-slice prospective gating cardiac CT SN - 0938-7994 PY - 2012/// KW - *Algorithms KW - *Coronary Angiography/mt [Methods] KW - *Coronary Artery Disease/ra [Radiography] KW - *Radiographic Image Interpretation, Computer-Assisted/mt [Methods] KW - *Tomography, X-Ray Computed/mt [Methods] KW - Adult KW - Aged KW - Cardiac-Gated Imaging Techniques KW - Female KW - Humans KW - Male KW - Middle Aged KW - Radiographic Image Enhancement/mt [Methods] KW - Reproducibility of Results KW - Sensitivity and Specificity KW - Young Adult KW - MedStar Health Research Institute KW - MedStar Heart & Vascular Institute KW - Journal Article N2 - CONCLUSIONS: Cardiac CT using hybrid iterative reconstruction yields higher CNR and better image quality than FBP; KEY POINTS: * Cardiac CT helps clinicians to assess patients with coronary artery disease * Hybrid iterative reconstruction provides improved cardiac CT image quality * Hybrid iterative reconstruction improves the number of assessable coronary segments * Hybrid iterative reconstruction improves interobserver agreement on cardiac CT; METHODS: Prospective cardiac CT images from 20 patients were analysed. Paired image sets were created using 3 reconstructions, i.e. filtered back projection (FBP) and moderate- and high-level iterative reconstructions. Quantitative parameters including CT-attenuation, noise, and contrast-to-noise ratio (CNR) were determined in both proximal- and distal coronary segments. Image quality was graded on a 4-point scale; OBJECTIVES: To evaluate the effect of hybrid iterative reconstruction on qualitative and quantitative parameters at 256-slice cardiac CT; RESULTS: Coronary CT attenuation values were similar for FBP, moderate- and high-level iterative reconstruction at 293 +/- 74-, 290 +/- 75-, and 283 +/- 78 Hounsfield units (HU), respectively. CNR was significantly higher with moderate- and high-level iterative reconstructions (10.9 +/- 3.5 and 18.4 +/- 6.2, respectively) than FBP (8.2 +/- 2.5) as was the visual grading of proximal vessels. Visualisation of distal vessels was better with high-level iterative reconstruction than FBP. The mean number of assessable segments among 289 segments was 245, 260, and 267 for FBP, moderate- and high-level iterative reconstruction, respectively; the difference between FBP and high-level iterative reconstruction was significant. Interobserver agreement was significantly higher for moderate- and high-level iterative reconstruction than FBP ER -