TY  - BOOK
AU  - Drescher, Gail S
TI  - AARC Clinical Practice Guideline: Effectiveness of Pharmacologic Airway Clearance Therapies in Hospitalized Patients
SN  - 0020-1324
PY  - 2015///
KW  - *Airway Management/mt [Methods]
KW  - *Mucociliary Clearance
KW  - *Respiratory System Agents/ct [Contraindications]
KW  - *Respiratory Therapy/mt [Methods]
KW  - Adolescent
KW  - Adult
KW  - Aerosols/ct [Contraindications]
KW  - Aged
KW  - Aged, 80 and over
KW  - Hospitalization
KW  - Humans
KW  - Middle Aged
KW  - Young Adult
KW  - MedStar Washington Hospital Center
KW  - Respiratory Therapy
KW  - Journal Article
KW  - Practice Guideline
N1  - Available online from MWHC library: 2003 - 2008, Available in print through MWHC library: 1999 - 2008
N2  - Aerosolized medications are used as airway clearance therapy to treat a variety of airway diseases. These guidelines were developed from a systematic review with the purpose of determining whether the use of these medications to promote airway clearance improves oxygenation and respiratory mechanics, reduces ventilator time and ICU stay, and/or resolves atelectasis/consolidation compared with usual care. Recombinant human dornase alfa should not be used in hospitalized adult and pediatric patients without cystic fibrosis. The routine use of bronchodilators to aid in secretion clearance is not recommended. The routine use of aerosolized N-acetylcysteine to improve airway clearance is not recommended. Aerosolized agents to change mucus biophysical properties or promote airway clearance are not recommended for adult or pediatric patients with neuromuscular disease, respiratory muscle weakness, or impaired cough. Mucolytics are not recommended to treat atelectasis in postoperative adult or pediatric patients, and the routine administration of bronchodilators to postoperative patients is not recommended. There is no high-level evidence related to the use of bronchodilators, mucolytics, mucokinetics, and novel therapy to promote airway clearance in these populations. Copyright © 2015 by Daedalus Enterprises
UR  - http://dx.doi.org/10.4187/respcare.04165
ER  -