TY - BOOK AU - Clark-Ganheart, Cecily A AU - Grantz, Katherine L AU - Huang, Chun Chih AU - Landy, Helain J AU - Reddy, Uma M TI - Pregnancy Outcomes Among Obese Women and Their Offspring by Attempted Mode of Delivery SN - 0029-7844 PY - 2015/// KW - *Delivery, Obstetric/sn [Statistics & Numerical Data] KW - *Obesity/co [Complications] KW - *Pregnancy Complications/ep [Epidemiology] KW - *Pregnancy Outcome/ep [Epidemiology] KW - Adult KW - Female KW - Humans KW - Pregnancy KW - Retrospective Studies KW - United States/ep [Epidemiology] KW - Young Adult KW - MedStar Health Research Institute KW - MedStar Washington Hospital Center KW - Obstetrics and Gynecology, Maternal-Fetal Medicine KW - Comparative Study KW - Journal Article KW - Multicenter Study KW - Research Support, N.I.H., Extramural KW - Research Support, N.I.H., Intramural N1 - Available online from MWHC library: 1995 - present, Available in print through MWHC library: 1999 - 2006 N2 - CONCLUSION: In obese nulliparous women, attempted vaginal delivery was not associated with increased composite maternal or neonatal morbidity. In obese parous women, attempted vaginal delivery was associated with increased composite maternal morbidity and lower composite neonatal morbidity; LEVEL OF EVIDENCE: II; METHODS: We performed a retrospective cohort study of 47,372 obese women at delivery (body mass index 30 or greater) eligible for vaginal delivery who were carrying singleton vertex fetuses at 37 weeks of gestation or greater. Prior cesarean delivery, congenital anomalies, and antepartum stillbirth were exclusion criteria. We analyzed outcomes by attempted delivery route and stratified by parity. The composite maternal outcome included intensive care admission, death, hemorrhage, transfusion, or thromboembolism. The neonatal composite included intensive care unit admission, death, seizure, ventilator use, birth injury, or asphyxia. Adjusted relative risks (RRs) and 95% confidence intervals (CIs) were calculated using Poisson regression; OBJECTIVE: To compare maternal and neonatal morbidities among obese women and their offspring by attempted delivery approach; RESULTS: Among nulliparous women attempting vaginal delivery (n=15,268), the success rate was 72.6% and among parous women (n=23,426), it was 93.7%. The maternal composite outcome rate was not statistically higher among nulliparous women (7.7% compared with 4.2% [adjusted RR 1.58, 95% CI 0.96-2.59]) but it was among parous women (7.6% compared with 2.5% [adjusted RR 2.45, 95% CI 1.23-4.90]) attempting vaginal delivery related to hemorrhage, blood transfusion, or both. In contrast, the neonatal composite outcome rate was lower in parous women (6.0% compared with 11.6% [adjusted RR 0.65, 95% CI 0.51-0.83]) but not in nulliparous women (10.2% compared with 12.4% [adjusted RR 0.91, 95% CI 0.74-1.12]) parous UR - http://dx.doi.org/10.1097/AOG.0000000000001084 ER -