TY  - BOOK
AU  - Asch, Federico M
AU  - Baker, Nevin C
AU  - Ben-Dor, Itsik
AU  - Didier, Romain
AU  - Escarcega, Ricardo O
AU  - Gaglia, Michael AJ
AU  - Jiaxiang, Gai
AU  - Kiramijyan, Starkis
AU  - Koifman, Edward
AU  - Magalhaes, Marco A
AU  - Minha, Sa'ar
AU  - Negi, Smita I
AU  - Okubagzi, Petros
AU  - Pichard, Augusto D
AU  - Satler, Lowell F
AU  - Torguson, Rebecca
AU  - Waksman, Ron
AU  - Wang, Zuyue
TI  - Aortic Regurgitation in Patients Undergoing Transcatheter Aortic Valve Replacement With the Self-Expanding CoreValve Versus the Balloon-Expandable SAPIEN XT Valve
SN  - 0002-9149
PY  - 2016///
KW  - *Aortic Valve Insufficiency/th [Therapy]
KW  - *Heart Valve Prosthesis/ae [Adverse Effects]
KW  - *Transcatheter Aortic Valve Replacement/ae [Adverse Effects]
KW  - Aged
KW  - Aged, 80 and over
KW  - Female
KW  - Hospitalization
KW  - Humans
KW  - Incidence
KW  - Logistic Models
KW  - Male
KW  - Prosthesis Design
KW  - Retrospective Studies
KW  - Severity of Illness Index
KW  - Treatment Outcome
KW  - MedStar Health Research Institute
KW  - MedStar Heart & Vascular Institute
KW  - Journal Article
N1  - Available online from MWHC library: 1995 - present, Available in print through MWHC library: 1999 - 2006
N2  - The incidence of aortic regurgitation (AR) after transcatheter aortic valve replacement (TAVR) in a self-expanding and a balloon-expandable system is controversial. This study aimed to examine the incidence and severity of post-TAVR AR with the CoreValve (CV) versus the Edwards XT Valve (XT). Baseline, procedural, and postprocedural inhospital outcomes were compared. The primary end point was the incidence of post-TAVR AR of any severity, assessed with a transthoracic echocardiogram, in the CV versus XT groups. A multivariate logistic regression analysis was completed to evaluate for correlates of the primary end point. The secondary end points included the change in severity of AR at 30-day and 1-year follow-up. A total of 223 consecutive patients (53% men, mean age 82 years) who had transfemoral TAVR with either a CV (n = 119) or XT (n = 104) were evaluated. The rates of post-TAVR AR in the groups were similar, and there was no evidence of more-than-moderate AR in either group. There were significant differences in the rates of intraprocedural balloon postdilation with the CV (17.1%) versus XT valve (5.8%; p = 0.009) and in the rates of intraprocedural implantation of a second valve-in-valve prosthesis with the CV (9.9%) versus XT valve (2.2%; p = 0.036). There were no significant differences in inhospital safety outcomes between the 2 groups. In conclusion, the incidence of post-TAVR AR is similar between the CV and the XT valve when performed by experienced operators using optimal intraprocedural strategies, as deemed appropriate, to mitigate the severity of AR.Copyright © 2016 Elsevier Inc. All rights reserved
UR  - http://dx.doi.org/10.1016/j.amjcard.2016.02.021
ER  -