TY  - BOOK
AU  - Damavandy, Ali Alexander
AU  - Skelsey, Maral Kibarian
TI  - Malignant Glomus Tumor Arising in a Long Standing Precursor Lesion
SN  - 0193-1091
PY  - 2016///
KW  - *Cell Transformation, Neoplastic
KW  - *Glomus Tumor/pa [Pathology]
KW  - *Skin Neoplasms/pa [Pathology]
KW  - Aged, 80 and over
KW  - Biomarkers, Tumor/an [Analysis]
KW  - Biopsy
KW  - Cell Proliferation
KW  - Female
KW  - Glomus Tumor/ch [Chemistry]
KW  - Glomus Tumor/su [Surgery]
KW  - Humans
KW  - Immunohistochemistry
KW  - Skin Neoplasms/ch [Chemistry]
KW  - Skin Neoplasms/su [Surgery]
KW  - Time Factors
KW  - Treatment Outcome
KW  - Tumor Burden
KW  - MedStar Washington Hospital Center
KW  - Dermatology
KW  - Case Reports
KW  - Journal Article
N1  - Available online from MWHC library: Feb 1996 - present
N2  - Malignant glomus tumor is an exceedingly rare vascular malignancy of unclear etiology, which is believed to arise de novo or from malignant transformation of a benign glomus tumor. The authors present a case of an elderly woman evaluated for a painful 2.5-cm purple-brown tumor on the right forearm that grew rapidly within a long-standing, seemingly benign lesion. An excisional biopsy revealed a multilobular dermal tumor composed of areas of benign-appearing glomus tumor cells interspersed with areas of dense, pleomorphic cells arranged in sheets and fascicles with an elevated mitotic rate. The diagnosis of malignant glomus tumor was made on the basis of the lesion's nuclear atypia and elevated mitotic rate. This case demonstrates malignant transformation of a presumably benign glomus tumor precursor lesion highlighting this rarely reported phenomenon. The authors present this case to raise awareness of this vascular malignancy that carries a significant risk of metastasis
UR  - https://dx.doi.org/10.1097/DAD.0000000000000481
ER  -