TY  - BOOK
AU  - Shorr, Andrew F
TI  - Epidemiology and Outcomes of Hospitalizations With Invasive Aspergillosis in the United States, 2009-2013
SN  - 1058-4838
PY  - 2018///
KW  - *Aspergillosis/mo [Mortality]
KW  - *Hospital Mortality
KW  - *Hospitalization/ec [Economics]
KW  - *Invasive Fungal Infections/ec [Economics]
KW  - *Invasive Fungal Infections/mo [Mortality]
KW  - Aged
KW  - Aged, 80 and over
KW  - Aspergillosis/ec [Economics]
KW  - Cost of Illness
KW  - Female
KW  - Humans
KW  - Length of Stay/ec [Economics]
KW  - Male
KW  - Middle Aged
KW  - Patient Discharge
KW  - Patient Outcome Assessment
KW  - Patient Readmission/sn [Statistics & Numerical Data]
KW  - Propensity Score
KW  - Retrospective Studies
KW  - United States/ep [Epidemiology]
KW  - MedStar Washington Hospital Center
KW  - Medicine/Pulmonary-Critical Care
KW  - Journal Article
N1  - Available online from MWHC library: June 1997 - present, Available in print through MWHC library: 1999 - Winter 2007
N2  - Background: Though invasive aspergillosis (IA) complicates care of up to 13% of patients with immunocompromise, little is known about its morbidity and mortality burden in the United States; Conclusions: Although rare even among high-risk groups, IA is associated with increased hospital mortality and 30-day readmission rates, excess duration of hospitalization, and costs. Given nearly 40000 annual admissions for IA in the United States, the aggregate IA-attributable excess costs may reach; Methods: We analyzed the Health Care Utilization Project's data from the Agency for Healthcare Research and Quality for 2009-2013. Among subjects with high-risk conditions for IA, IA was identified via International Classification of Diseases, Ninth Revision, Clinical Modification codes 117.3, 117.9, and 484.6. We compared characteristics and outcomes between those with (IA) and without IA (non-IA). Using propensity score matching, we calculated the IA-associated excess mortality and 30-day readmission rates, length of stay, and costs; Results: Of the 66634683 discharged patients meeting study inclusion criteria, 154888 (0.2%) had a diagnosis of IA. The most common high-risk conditions were major surgery (50.1%) in the non-IA and critical illness (41.0%) in the IA group. After propensity score matching, both mortality (odds ratio, 1.43; 95% confidence interval, 1.36-1.51) and 30-day readmission (1.39; 1.34-1.45) rates were higher in the IA group. IA was associated with 6.0 (95% confidence interval, 5.7-6.4) excess days in the hospital and
UR  - https://dx.doi.org/10.1093/cid/ciy181
ER  -