TY  - BOOK
AU  - Lapumnuaypol, Kamolyut
TI  - Gastrointestinal Bleeding among Hospitalizations for Salicylate Poisoning in the United States
SN  - 1460-2393
PY  - 2021///
KW  - *Gastrointestinal Hemorrhage
KW  - *Hospitalization
KW  - Databases, Factual
KW  - Gastrointestinal Hemorrhage/ci [Chemically Induced]
KW  - Hospital Mortality
KW  - Humans
KW  - Retrospective Studies
KW  - Salicylates
KW  - United States
KW  - MedStar Washington Hospital Center
KW  - Medicine/Gastroenterology
KW  - Journal Article
N1  - Available online from MWHC library: 1995 - present
N2  - BACKGROUND: This study aimed to determine the incidence, as well as evaluate risk factors, and impact of gastrointestinal bleeding on outcomes and resource use in patients admitted for salicylate poisoning; CONCLUSION: Gastrointestinal bleeding occurred in about 4% of patients admitted for salicylate poisoning. Gastrointestinal bleeding was associated with higher morbidity and resource use but not mortality. Copyright (c) The Author(s) 2021. Published by Oxford University Press on behalf of the Association of Physicians. All rights reserved. For Permissions, please email: journals.permissions@oup.com; METHODS: We used the National Inpatient Sample to construct a cohort of patients hospitalized primarily for salicylate poisoning from 2003-2014. We compared clinical characteristics, in-hospital treatments, outcomes, and resource use between salicylate poisoning patients with and without gastrointestinal bleeding; RESULTS: Of 13,805 hospital admissions for salicylate poisoning, gastrointestinal bleeding occurred in 482 (3.5%) admissions. The risk factors for gastrointestinal bleeding included older age, history of atrial fibrillation, and cirrhosis. After adjusting for difference in baseline characteristics, patients with gastrointestinal bleeding required more gastric lavage, gastrointestinal endoscopy, invasive mechanical ventilation, red blood cell transfusion. Gastrointestinal bleeding was significantly associated with increased risk of anemia, circulatory, liver, and hematological failure but was not significantly associated with increased in-hospital mortality. The length of hospital stay and hospitalization cost was significantly higher in patients with gastrointestinal bleeding
UR  - https://dx.doi.org/10.1093/qjmed/hcab034
ER  -