TY  - BOOK
AU  - Zaaqoq, Akram M
TI  - Beneficial Effect of Prone Positioning During Venovenous Extracorporeal Membrane Oxygenation for Coronavirus Disease 2019
SN  - 0090-3493
PY  - 2022///
KW  - *COVID-19/th [Therapy]
KW  - *Extracorporeal Membrane Oxygenation
KW  - *Patient Positioning/mt [Methods]
KW  - *Prone Position
KW  - *Respiratory Distress Syndrome/th [Therapy]
KW  - *SARS-CoV-2
KW  - Adult
KW  - COVID-19/co [Complications]
KW  - Female
KW  - Hospital Mortality
KW  - Humans
KW  - Male
KW  - Middle Aged
KW  - Patient Discharge
KW  - Probability
KW  - Respiratory Distress Syndrome/et [Etiology]
KW  - MedStar Washington Hospital Center
KW  - Medicine/Pulmonary-Critical Care
KW  - Journal Article
N2  - CONCLUSIONS: Our study highlights that prone positioning during venovenous extracorporeal membrane oxygenation support for refractory coronavirus disease 2019-related acute respiratory distress syndrome is associated with reduced mortality. Given the observational nature of the study, a randomized controlled trial of prone positioning on venovenous extracorporeal membrane oxygenation is needed to confirm these findings. Copyright (c) by 2021 by the Society of Critical Care Medicine and Wolters Kluwer Health, Inc. All Rights Reserved; DESIGN: An observational study of venovenous extracorporeal membrane oxygenation patients. We used a multistate survival model to compare the outcomes of patients treated with or without prone positioning during extracorporeal membrane oxygenation, which incorporates the dynamic nature of prone positioning and adjusts for potential confounders; INTERVENTION: None; MEASUREMENTS AND MAIN RESULTS: There were 232 coronavirus disease 2019 patients at 72 participating institutions who were supported with venovenous extracorporeal membrane oxygenation during the study period from February 16, 2020, to October 31, 2020. Proning was used in 176 patients (76%) before initiation of extracorporeal membrane oxygenation and in 67 patients (29%) during extracorporeal membrane oxygenation. Survival to hospital discharge was 33% in the extracorporeal membrane oxygenation prone group versus 22% in the extracorporeal membrane oxygenation supine group. Prone positioning during extracorporeal membrane oxygenation support was associated with reduced mortality (hazard ratio, 0.31; 95% CI, 0.14-0.68); OBJECTIVES: The study investigated the impact of prone positioning during venovenous extracorporeal membrane oxygenation support for coronavirus disease 2019 acute respiratory failure on the patient outcome; PATIENTS: Coronavirus disease 2019 patients who were supported by venovenous extracorporeal membrane oxygenation during the study period; SETTING: Seventy-two international institutions participating in the Coronavirus Disease 2019 Critical Care Consortium international registry
UR  - https://dx.doi.org/10.1097/CCM.0000000000005296
ER  -