The effect of catheter-directed thrombolytic use on readmission rates and in-hospital outcomes among cancer patients with venous thromboembolism in the United States.
Citation: Journal of Cardiac Surgery. 35(3):609-611, 2020 Mar.PMID: 32017181Institution: MedStar Heart & Vascular Institutena | MedStar Washington Hospital CenterDepartment: Medicine/Internal MedicineForm of publication: Journal ArticleMedline article type(s): Journal ArticleSubject headings: *Hospital Mortality | *Mechanical Thrombolysis/ae [Adverse Effects] | *Mechanical Thrombolysis/mt [Methods] | *Neoplasms/co [Complications] | *Patient Readmission/sn [Statistics & Numerical Data] | *Venous Thromboembolism/mo [Mortality] | *Venous Thromboembolism/th [Therapy] | Catheters | Cohort Studies | Costs and Cost Analysis | Female | Humans | Male | Middle Aged | United States/ep [Epidemiology] | Venous Thromboembolism/ec [Economics]Year: 2020ISSN:- 0886-0440
Item type | Current library | Collection | Call number | Status | Date due | Barcode |
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Journal Article | MedStar Authors Catalog | Article | 32017181 | Available | 32017181 |
BACKGROUND: Cancer inducing a hypercoagulable state, venous thromboembolism (VTE) remains a leading cause of morbidity and mortality globally. We assessed the impacts of cancer on the likelihood for readmission after a VTE-targeted procedure.
CONCLUSION: The use of CDL does not appear to reduce the risk of returning for a VTE-related admission in cancer. Copyright (c) 2020 Wiley Periodicals, Inc.
METHODS: We created a new cohort using discharge-level data from all hospitalizations from State Inpatient Databases of geographically dispersed participating states (18-27 states).
RESULTS: In those presenting with VTE during index-admission (619 241), 2.4% patients underwent catheter directed thrombolytic therapy (CDL) on index admission and among those 20.3% had cancer. Moreover, the 30-day readmission rate amongst CDL recipients (10 776 overall) was 14.3% in those with cancer compared to 8.8% in those with no cancer history (P < .0001). Additionally, in-hospital mortality (5.7% vs 1.1%; P = 0.009) and cost-of-care ( 1 014 +/- 914 vs 0 520 +/- 534; P = .04) was significantly higher in cancer compared to noncancer.
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