Neurogenic Stunned Myocardium in Severe Neurological Injury. [Review]
Citation: Current Neurology & Neuroscience Reports. 19(11):90, 2019 11 13.PMID: 31720870Institution: MedStar Heart & Vascular Institute | MedStar Washington Hospital CenterDepartment: Neurosurgery | Surgery/Surgical Critical CareForm of publication: Journal ArticleMedline article type(s): Journal Article | ReviewSubject headings: *Donor Selection/mt [Methods] | *Myocardial Stunning | Acute Coronary Syndrome/di [Diagnosis] | Diagnosis, Differential | Humans | Myocardial Stunning/di [Diagnosis] | Myocardial Stunning/ep [Epidemiology] | Myocardial Stunning/pp [Physiopathology] | Myocardial Stunning/th [Therapy]Year: 2019ISSN:- 1528-4042
Item type | Current library | Collection | Call number | Status | Date due | Barcode |
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Journal Article | MedStar Authors Catalog | Article | 31720870 | Available | 31720870 |
PURPOSE OF REVIEW: Neurogenic stunned myocardium (NSM) is a poorly recognized cardiac manifestation of neurological illness. This review addresses the contemporary understanding of NSM pathophysiology, epidemiology, diagnosis, and clinical management.
RECENT FINDINGS: While the precise pathophysiology and diagnosis remain unclear, NSM is phenotypically atypical stress cardiomyopathy that can be partially attributed to excess catecholaminergic toxicity. NSM is a diagnosis of exclusion where electrocardiography, echocardiography, and cardiac biomarkers are frequently abnormal. Clinical expertise is crucial to evaluate and differentiate NSM from acute coronary syndrome and in the evaluation of potential cardiac transplantation donors after unsalvageable severe neurological injury. Neurogenic stunned myocardium is a relatively common and clinically impactful condition. More research is needed, particularly to refine clinical prognostication of NSM and rule out intrinsic cardiac injury in order to optimize donor candidacy in the event of brain death.
English